uses sweetener sorbitol is actually a sugar substitute it might be listed under the inactive ingredients listed for some foods and merchandise sorbitol is referred to as a nutritive sweetener because it provides dietary energy 2 6 kilocalories 11 kilojoules per gram versus the average 4 kilocalories 17 kilojoules for carbohydrates issues is needed in diet foods including diet drinks and soft ice cream mints cough syrups and sugar free nicotine gum additionally,
nfl store, it occurs naturally in many stone fruits and berries from trees of one's genus sorbus laxative sorbitol should be considered as a non stimulant laxative with an oral suspension or enema it is used by drawing water into your large intestine thereby stimulating bowel motions sorbitol happens to be determined safe for replacements from the elderly is usually is just not recommended without consultation accompanied by a clinician medical applications sorbitol must be used in bacterial culture media to differentiate escherichia coli 0154 h7 from most other strains of e coli citation needed sorbitol blended with kayexalate helps your system rid itself of excess potassium ions with a hyperkalaemic state the kayexalate exchanges sodium ions for potassium ions around the bowel while sorbitol can help to eliminate it health-related food and cosmetic uses sorbitol often is commonly used in modern cosmetics as being a humectant and thickener citation needed sorbitol often is employed in mouthwash and toothpaste some transparent gels can be produced only with sorbitol given it posesses a refractive index sufficiently high for transparent formulations sorbitol is needed to provide a cryoprotectant additive mixed with sucrose and sodium polyphosphates while in the output of surimi the highly refined fish paste most frequently composed of alaska or walleye pollock theragra chalcogramma citation needed it is also used being a humectant some cigarettes sorbital sometimes may be used to provide a sweetener and humectant in cookies besides other foods that aren't defined as dietary items medical importance during the absence of dietary sorbitol cells produce sorbitol naturally a lot of sorbitol trapped in eye and nerve cells may damage these cells which causes retinopathy and neuropathy substances that prevent or slow the act of aldose reductase are now being studied in order to prevent or delay these complications of diabetes aldose reductase certainly is the first enzyme within the sorbitol pathway this pathway is liable for the conversion of glucose to sorbitol as well as galactose to galactitol under conditions of hyperglycemia sorbitol accumulation occurs aldose reductase inhibitors steer clear of the accumulation of intracellular sorbitol sensitivity to the substance may provide severe pain among people that are intolerant of computer and exhibit adverse symptoms from sorbitol diabetic retinopathy and neuropathy could very well be related to excess sorbitol within the cells on the eyes and nerves the foundation of these sorbitol in diabetics is excess glucose which fits with the sorbitol aldose reductase pathway using some human enzyme deficiencies which includes galactosemia sorbitol excess arises which enables it to can damage your system in diabetes enzyme deficiency while in the lens from the eye may cause sorbitol accumulation and cataracts citation needed adverse medical effects sorbitol also may aggravate irritable bowel syndrome and other gastrointestinal conditions contributing to severe abdominal pain for people affected even from small amounts ingested overdose effects ingesting large measures of sorbitol can bring about abdominal pain gas and mild to severe diarrhea citation needed sorbitol ingestion of 20 160 grams 0 7 160 oz everyday as sugar free gum has caused severe diarrhea resulting in unintended losing weight of 11 160 kilograms 24 160 lb within a woman originally weighing 52 160 kilograms 110 160 lb another patient required hospitalization after habitually consuming 30 160 grams 1 160 oz daily compendial status food chemical codex european pharmacopoeia 6 1 itish pharmacopoeia 2009 japanese pharmacopoeia 15 citation needed miscellaneous operates on the all mixture of sorbitol and potassium nitrate has found some success if you are an amateur solid rocket fuel sorbitol is recognized as a potential key chemical intermediate from biomass resources complete lowering of sorbitol opens the way to alkanes including hexane that may be used to be a biofuel sorbitol itself provides a great deal of the hydrogen necessary the transformation 19 c6h14o6 13 c6h14 36 co2 42 h2o search of a chemical reaction is exothermic 1 5 mole of sorbitol generates approximately 1 mole of hexane when hydrogen is co fed no fractional co2 is produced see also mannitol mouthwash xylitol external links nih diabetes dictionary see entry on sorbitol notes and references lehninger principles of biochemistry nelson and cox fourth edition acs 160 cancer drug guide sorbitol lederle fa epidemiology of constipation in elderly patients drug utilization and cost containment strategies drugs and ageing 6 465 469 1995 rugolotto s gruber m solano pd chini l gobbo s pecori s april 2007 necrotizing enterocolitis in a very 850 gram infant receiving sorbitol free sodium polystyrene sulfonate kayexalate clinical and histopathologic findings j perinatol 27 4 2479 doi 10 1038 sj jp 7211677 pmid 17377608 160 gallaher group plc ingredients sorbitol a hazard for diabetics nutrition health review normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage ibs causes and treatment what can aggravate my symptoms kathleen doheny 2008 01 10 sweetener unintended effects case histories webmd medical news http www webmd com diet news 20080110 sweetener side effects case histories retrieved 2008 01 10 160 the states pharmacopeial convention revisions to fcc first supplement http www usp org fcc fcc61sballotresultswebpostingreport04 html retrieved 6 july 2009 160 sigma aldrich d sorbitol http www sigmaaldrich com catalog productdetail do lang en amp n4 97336 retrieved 6 july 2009 160 european pharmacopoeia index ph eur https www edqm eu store images majbdd 200709201618250 6_1 20indexe pdf retrieved 6 july 2009 160 itish pharmacopoeia 2009 index bp 2009 http www pharmacopoeia co uk pdf 2009_index pdf retrieved 6 july 2009 160 richard nakka s experimental rocketry internet site production of liquid hydrocarbons from biomass jrgen o metzger angewandte chemie international edition volume 45 issue 5 pages 696 698 2005 hyperlink to the publisher br v 160 160 d 160 160 e br laxatives and cathartics a06 br softeners emollients br paraffin 160 docusate sodium br contact laxatives br oxyphenisatine 160 bisacodyl 160 dantron 160 phenolphthalein 160 castor oil treatment 160 senna glycosides 160 cascara 160 sodium picosulfate 160 bisoxatin br bulk producers br ispaghula 160 ethulose 160 sterculia 160 linseed 160 methylcellulose 160 triticum 160 polycarbophil calcium br osmotically acting laxatives br magnesium carbonate 160 magnesium oxide 160 magnesium peroxide 160 magnesium sulfate 160 lactulose 160 lactitol 160 sodium sulfate 160 pentaerythritol 160 macrogol 160 mannitol 160 sodium phosphate 160 sorbitol 160 magnesium citrate 160 sodium tartrate br enemas br sodium laurilsulfate 160 sodium phosphate 160 bisacodyl 160 dantron 160 glycerol 160 oil 160 sorbitol br 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vitamin concentrates br bile duct patency br sorbitol 160 magnesium sulfate 160 sincalide 160 ceruletide br liver functional capacity br galactose 160 sulfobromophthalein br gastric secretion br cation exchange resins 160 betazole 160 histamine phosphate 160 pentagastrin 160 methylthioninium chloride 160 caffeine and sodium benzoate br exocrine pancreatic function br secretin 160 pancreozymin cholecystokinin 160 bentiromide br endocrine system br pituitary function br cortisol metyrapone 160 corticorelin br gh sermorelin 160 somatorelin br thyroid function br thyrotropin 160 protirelin br fertility disturbances br gonadorelin br tuberculosis br tuberculin br renal function br inulin as well as other polyfructosans 160 indigo carmine 160 phenolsulfonphthalein 160 alsactide 160 aminohippuric acid br categories osmotic diuretics sugar alcohols sweeteners excipientshidden categories chemboxes that may contain changes to watched fields articles needing additional references from july 2009 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